Sarcoplasmic Reticulum K(+) (TRIC) Channel Does Not Carry Essential Countercurrent during Ca(2+) Release

The charge translocation associated with sarcoplasmic reticulum (SR) Ca(2+) efflux is compensated for by a simultaneous SR K(+) influx. This influx is essential because, with no countercurrent, the SR membrane potential (V(m)) would quickly (<1 ms) reach the Ca(2+) equilibrium potential and SR Ca...

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Hlavní autoři: Guo, Tao, Nani, Alma, Shonts, Stephen, Perryman, Matthew, Chen, Haiyan, Shannon, Thomas, Gillespie, Dirk, Fill, Michael
Médium: Artigo
Jazyk:Inglês
Vydáno: The Biophysical Society 2013
Témata:
Channels and Transporters
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3762336/
https://ncbi.nlm.nih.gov/pubmed/24010658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.07.042
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