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Metformin Suppresses MHC-Restricted Antigen Presentation by Inhibiting Co-Stimulatory Factors and MHC Molecules in APCs

Metformin is widely used for T2D therapy but its cellular mechanism of action is undefined. Recent studies on the mechanism of metformin in T2D have demonstrated involvement of the immune system. Current immunotherapies focus on the potential of immunomodulatory strategies for the treatment of T2D....

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Shin, Seulmee, Hyun, Bobae, Lee, Aeri, Kong, Hyunseok, Han, Shinha, Lee, Chong-Kil, Ha, Nam-Joo, Kim, Kyungjae
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: The Korean Society of Applied Pharmacology 2013
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3762296/
https://ncbi.nlm.nih.gov/pubmed/24009856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4062/biomolther.2012.094
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