Kupffer cell and Interleukin-12 Dependent Loss of Natural Killer T cells in Hepatosteatosis

BACKGROUND: Hepatosteatosis is associated with increased expression of tumor necrosis factor alpha (TNFα) and interleukin (IL)-12, major T helper (Th) 1 cytokines, and reduced hepatic NKT cell numbers. The relationship between lipid accumulation, cytokine expression, and hepatic NKT cells is not kno...

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Main Authors: Kremer, Michael, Thomas, Emmanuel, Milton, Richard J., Perry, Ashley W., van Rooijen, Nico, Wheeler, Michael D., Zacks, Steven, Fried, Michael, Rippe, Richard A., Hines, Ian N.
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3761962/
https://ncbi.nlm.nih.gov/pubmed/20034047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.23292
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