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(11)C-(R)-PK11195 PET Imaging of Microglial Activation and Response to Minocycline in Zymosan-Treated Rats

We sought to advance methodology for studying microglial activation and putative therapeutic downregulation in response to minocycline by means of noninvasive in vivo imaging. A reproducible focal white matter lesion was used to reliably compare treatment conditions. METHODS: The corpus callosum of...

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Detalhes bibliográficos
Main Authors: Converse, Alexander K., Larsen, Eric C., Engle, Jonathan W., Barnhart, Todd E., Nickles, Robert J., Duncan, Ian D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3761794/
https://ncbi.nlm.nih.gov/pubmed/21233178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.110.082743
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