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Progesterone facilitates exploration, affective and social behaviors among wildtype, but not 5α-reductase Type 1 mutant, mice

Progesterone (P(4)) facilitates exploration, anxiety and social behaviors in estrogen (E(2))-primed mice. Some of these effects may be due to actions of its 5α-reduced metabolite, 5α-pregnan-3α-ol-20-one (3α,5α-THP). In order to address the role of P(4) and its metabolite, 3α,5α-THP, a mouse model w...

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Detalhes bibliográficos
Main Authors: Koonce, Carolyn J., Frye, Cheryl A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3761366/
https://ncbi.nlm.nih.gov/pubmed/23886595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbr.2013.07.025
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