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Protein kinase C-α interaction with iHSP70 in mitochondria promotes recovery of mitochondrial function after injury in renal proximal tubular cells

This study determined the role of PKC-α and associated inducible heat shock protein 70 (iHSP70) in the repair of mitochondrial function in renal proximal tubular cells (RPTCs) after oxidant injury. Wild-type PKC-α (wtPKC-α) and an inactive PKC-α [dominant negative dn; PKC-α] mutant were overexpresse...

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Hlavní autoři: Nowak, Grazyna, Soundararajan, Sridharan, Mestril, Ruben
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3761207/
https://ncbi.nlm.nih.gov/pubmed/23804450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00061.2013
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