Hindbrain GLP-1 receptor-mediated suppression of food intake requires a PI3K-dependent decrease in phosphorylation of membrane-bound Akt

Glucagon-like peptide-1 (GLP-1) receptors (GLP-1R) expressed in the nucleus tractus solitarius (NTS) are physiologically required for the control of feeding. Recently, NTS GLP-1R-mediated suppression of feeding was shown to occur via a rapid PKA-induced suppression of AMPK and activation of MAPK sig...

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Autors principals: Rupprecht, Laura E., Mietlicki-Baase, Elizabeth G., Zimmer, Derek J., McGrath, Lauren E., Olivos, Diana R., Hayes, Matthew R.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2013
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3761195/
https://ncbi.nlm.nih.gov/pubmed/23900416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00367.2013
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