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A randomized phase 2a efficacy and safety trial of the topical Janus kinase inhibitor tofacitinib in the treatment of chronic plaque psoriasis

BACKGROUND: Tofacitinib (CP-690,550) is a novel Janus kinase inhibitor in development as an oral formulation for the treatment of several inflammatory diseases including psoriasis. OBJECTIVES: This phase 2a study aimed to assess the efficacy, systemic safety, local tolerability and systemic pharmaco...

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Autori principali: Ports, WC, Khan, S, Lan, S, Lamba, M, Bolduc, C, Bissonnette, R, Papp, K
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Publishing Ltd 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3761190/
https://ncbi.nlm.nih.gov/pubmed/23387374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bjd.12266
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