Mechanisms underlying activation of transient BK current in rabbit urethral smooth muscle cells and its modulation by IP(3)-generating agonists

We used the perforated patch-clamp technique at 37°C to investigate the mechanisms underlying the activation of a transient large-conductance K(+) (tBK) current in rabbit urethral smooth muscle cells. The tBK current required an elevation of intracellular Ca(2+), resulting from ryanodine receptor (R...

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Autori principali: Kyle, Barry D., Bradley, Eamonn, Large, Roddy, Sergeant, Gerard P., McHale, Noel G., Thornbury, Keith D., Hollywood, Mark A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2013
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3761171/
https://ncbi.nlm.nih.gov/pubmed/23804200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00025.2013
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