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Trehalose prevents neural tube defects by correcting maternal diabetes-suppressed autophagy and neurogenesis

Preexisting maternal diabetes increases the risk of neural tube defects (NTDs). The mechanism underlying maternal diabetes-induced NTDs is not totally defined, and its prevention remains a challenge. Autophagy, an intracellular process to degrade dysfunction protein and damaged cellular organelles,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Xu, Cheng, Li, Xuezheng, Wang, Fang, Weng, Hongbo, Yang, Peixin
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3761168/
https://ncbi.nlm.nih.gov/pubmed/23880312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00185.2013
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