Genome-wide association and meta-analysis in populations from Starr County, Texas, and Mexico City identify type 2 diabetes susceptibility loci and enrichment for expression quantitative trait loci in top signals

AIMS/HYPOTHESIS: We conducted genome-wide association studies (GWASs) and expression quantitative trait loci (eQTL) analyses to identify and characterise risk loci for type 2 diabetes in Mexican-Americans from Starr County, TX, USA. METHOD: Using 1.8 million directly interrogated and imputed genotyp...

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Autori principali: Below, J. E., Gamazon, E. R., Morrison, J. V., Konkashbaev, A., Pluzhnikov, A., McKeigue, P. M., Parra, E. J., Elbein, S. C., Hallman, D. M., Nicolae, D. L., Bell, G. I., Cruz, M., Cox, N. J., Hanis, C. L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3761075/
https://ncbi.nlm.nih.gov/pubmed/21647700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-011-2188-3
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