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Protein kinase C, an elusive therapeutic target?
Protein kinase C (PKC) has been a tantalizing target for drug discovery ever since it was first identified as the receptor for the tumor promoter phorbol ester in 1982(1). Although initial therapeutic efforts focused on cancer, additional diseases, including diabetic complications, heart failure, my...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3760692/ https://ncbi.nlm.nih.gov/pubmed/23197040 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrd3871 |
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