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Isolation of Bacteriophage T4 Mutants Defective in the Ability to Degrade Host Deoxyribonucleic Acid

A method was devised for identifying nonlethal mutants of T4 bacteriophage which lack the capacity to induce degradation of the deoxyribonucleic acid (DNA) of their host, Escherichia coli. If a culture is infected in a medium containing hydroxyurea (HU), a compound that blocks de novo deoxyribonucle...

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Udgivet i:J Virol
Principais autores: Warner, Huber R., Snustad, D. Peter, Jorgensen, Sally E., Koerner, James F.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1970
Fag:
Bacterial Viruses
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC376063/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4914096/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.5.6.700-708.1970
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