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Manipulating the sleep-wake cycle and circadian rhythms to improve clinical management of major depression

BACKGROUND: Clinical psychiatry has always been limited by the lack of objective tests to substantiate diagnoses and a lack of specific treatments that target underlying pathophysiology. One area in which these twin failures has been most frustrating is major depression. Due to very considerable pro...

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Detalhes bibliográficos
Main Authors: Hickie, Ian B, Naismith, Sharon L, Robillard, Rébecca, Scott, Elizabeth M, Hermens, Daniel F
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3760618/
https://ncbi.nlm.nih.gov/pubmed/23521808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1741-7015-11-79
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