Drebrin contains a cryptic F-actin–bundling activity regulated by Cdk5 phosphorylation

Drebrin is an actin filament (F-actin)–binding protein with crucial roles in neuritogenesis and synaptic plasticity. Drebrin couples dynamic microtubules to F-actin in growth cone filopodia via binding to the microtubule-binding +TIP protein EB3 and organizes F-actin in dendritic spines. Precisely h...

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Autores principales: Worth, Daniel C., Daly, Catherine N., Geraldo, Sara, Oozeer, Fazal, Gordon-Weeks, Phillip R.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2013
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3760615/
https://ncbi.nlm.nih.gov/pubmed/23979715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201303005
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