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Adaptation to the spindle checkpoint is regulated by the interplay between Cdc28/Clbs and PP2A(Cdc55)
The spindle checkpoint arrests cells in metaphase until all chromosomes are properly attached to the chromosome segregation machinery. Thereafter, the anaphase promoting complex (APC/C) is activated and chromosome segregation can take place. Cells remain arrested in mitosis for hours in response to...
Tallennettuna:
| Päätekijät: | , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
The Rockefeller University Press
2013
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3760609/ https://ncbi.nlm.nih.gov/pubmed/23999167 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201303033 |
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