Evaluation of Normalization Methods to Pave the Way Towards Large-Scale LC-MS-Based Metabolomics Profiling Experiments

Combining liquid chromatography-mass spectrometry (LC-MS)-based metabolomics experiments that were collected over a long period of time remains problematic due to systematic variability between LC-MS measurements. Until now, most normalization methods for LC-MS data are model-driven, based on intern...

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Detalhes bibliográficos
Main Authors: Ejigu, Bedilu Alamirie, Valkenborg, Dirk, Baggerman, Geert, Vanaerschot, Manu, Witters, Erwin, Dujardin, Jean-Claude, Burzykowski, Tomasz, Berg, Maya
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2013
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3760460/
https://ncbi.nlm.nih.gov/pubmed/23808607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/omi.2013.0010
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