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Developmental roles of Drosophila tRNA processing endonuclease RNase Z(L) as revealed with a conditional rescue system

Drosophila RNase Z(L) (dRNaseZ) belongs to a family of endoribonucleases with a major role in tRNA 3′-end processing. The biochemical function of RNase Z(L) is conserved from yeast to human. Here we present a study of its biological function during Drosophila development. In flies, dRNaseZ provides...

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Detalhes bibliográficos
Main Authors: Xie, Xie, Dubrovskaya, Veronica, Yacoub, Nancy, Walska, Joanna, Gleason, Tara, Reid, Katherine, Dubrovsky, Edward B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3760340/
https://ncbi.nlm.nih.gov/pubmed/23867108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2013.07.005
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