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Sequential Checkpoints Govern Substrate Selection During Cotranslational Protein Targeting
Proper protein localization is essential for all cells. However, the precise mechanism by which high fidelity is achieved is not well understood for any targeting pathway. To address this fundamental question we investigated the signal recognition particle (SRP) pathway in E. coli, which delivers pr...
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| Main Authors: | , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2010
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3760334/ https://ncbi.nlm.nih.gov/pubmed/20448185 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1186743 |
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