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Quantitative metrics of net proliferation and invasion link biological aggressiveness assessed by MRI with hypoxia assessed by FMISO-PET in newly diagnosed glioblastomas

Glioblastoma multiforme (GBM) are aggressive and uniformly fatal primary brain tumors characterized by their diffuse invasion of the normal appearing parenchyma peripheral to the clinical imaging abnormality. Hypoxia, a hallmark of aggressive tumor behavior often noted in GBMs, has been associated w...

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Detalhes bibliográficos
Main Authors: Szeto, Mindy D., Chakraborty, Gargi, Hadley, Jennifer, Rockne, Russ, Muzi, Mark, Alvord, Ellsworth C., Krohn, Kenneth A., Spence, Alexander M., Swanson, Kristin R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3760276/
https://ncbi.nlm.nih.gov/pubmed/19366800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-3884
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