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PI3K regulates branch initiation and extension of cultured mammary epithelia via Akt and Rac1 respectively
The tree-like architecture of the mammary gland is generated by branching morphogenesis, which is regulated by many signals from the microenvironment. Here we examined how signaling downstream of phosphoinositide 3-kinase (PI3K) regulates different steps of mammary branching using three-dimensional...
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| Main Authors: | , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2013
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3760257/ https://ncbi.nlm.nih.gov/pubmed/23665174 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2013.04.029 |
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