Human Primary Corneal Fibroblasts Synthesize and Deposit Proteoglycans in Long-Term 3-D Cultures

Our goal was to develop a 3-D multi-cellular construct using primary human corneal fibroblasts cultured on a disorganized collagen substrate in a scaffold-free environment and to use it to determine the regulation of proteoglycans over an extended period of time (11 weeks). Electron micrographs reve...

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Bibliographic Details
Main Authors: Ren, R., Hutcheon, A.E.K., Guo, X.Q., Saeidi, N., Melotti, S.A., Ruberti, J.W., Zieske, J.D., Trinkaus-Randall, V.
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3760227/
https://ncbi.nlm.nih.gov/pubmed/18624285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.21606
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