Deletion and Gene Expression Analyses Define the Paxilline Biosynthetic Gene Cluster in Penicillium paxilli

The indole-diterpene paxilline is an abundant secondary metabolite synthesized by Penicillium paxilli. In total, 21 genes have been identified at the PAX locus of which six have been previously confirmed to have a functional role in paxilline biosynthesis. A combination of bioinformatics, gene expre...

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Detalhes bibliográficos
Main Authors: Scott, Barry, Young, Carolyn A., Saikia, Sanjay, McMillan, Lisa K., Monahan, Brendon J., Koulman, Albert, Astin, Jonathan, Eaton, Carla J., Bryant, Andrea, Wrenn, Ruth E., Finch, Sarah C., Tapper, Brian A., Parker, Emily J., Jameson, Geoffrey B.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3760044/
https://ncbi.nlm.nih.gov/pubmed/23949005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins5081422
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