Regulation of Tcf7l1 DNA Binding and Protein Stability as Principal Mechanisms of Wnt/β-Catenin Signaling

Wnt/β-catenin signal transduction requires direct binding of β-catenin to Tcf/Lef proteins, an event that is classically associated with stimulating transcription by recruiting coactivators. This molecular cascade plays critical roles throughout embryonic development and normal postnatal life by aff...

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Hauptverfasser: Shy, Brian R., Wu, Chun-I., Khramtsova, Galina F., Zhang, Jenny Y., Olopade, Olufunmilayo I., Goss, Kathleen H., Merrill, Bradley J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3759994/
https://ncbi.nlm.nih.gov/pubmed/23810553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.06.001
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