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Design, Synthesis and DNA Interaction Study of New Potential DNA Bis-Intercalators Based on Glucuronic Acid

A series of novel potential DNA bis-intercalators were designed and synthesized, in which two glucuronic acids were linked by ethylenediamine, and the glucuronic acid was coupled with various chromophores, including quinoline, acridine, indole and purine, at the C-1 position. The preliminary binding...

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Main Authors: Zhao, Jiuyang, Li, Wei, Ma, Rui, Chen, Shaopeng, Ren, Sumei, Jiang, Tao
格式: Artigo
語言:Inglês
出版: MDPI 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3759939/
https://ncbi.nlm.nih.gov/pubmed/23955268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms140816851
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