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Optical clearing-aided photoacoustic microscopy with enhanced resolution and imaging depth

Due to strong light scattering in tissue, both the spatial resolution and maximum penetration depth of optical-resolution photoacoustic microscopy (OR-PAM) deteriorate sharply with depth. To reduce tissue scattering, we propose to use glycerol as an optical clearing agent in OR-PAM. Our results show...

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Detalhes bibliográficos
Main Authors: Zhou, Yong, Yao, Junjie, Wang, Lihong V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3759812/
https://ncbi.nlm.nih.gov/pubmed/23939121
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