Enhancement of microhomology-mediated genomic rearrangements by transient loss of mouse Bloom syndrome helicase

Bloom syndrome, an autosomal recessive disorder of the BLM gene, confers predisposition to a broad spectrum of early-onset cancers in multiple tissue types. Loss of genomic integrity is a primary hallmark of such human malignancies, but many studies using disease-affected specimens are limited in th...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Yamanishi, Ayako, Yusa, Kosuke, Horie, Kyoji, Tokunaga, Masahiro, Kusano, Kohji, Kokubu, Chikara, Takeda, Junji
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Cold Spring Harbor Laboratory Press 2013
Aiheet:
Research
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3759722/
https://ncbi.nlm.nih.gov/pubmed/23908384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.152744.112
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia