The Soluble Form of the Cellular Prion Protein Enhances Phagocytic Activity and Cytokine Production by Human Monocytes Via Activation of ERK and NF-κB

The PrP(C) is expressed in many types of immune cells including monocytes and macrophages, however, its function in immune regulation remains to be elucidated. In the present study, we examined a role for PrP(C) in regulation of monocyte function. Specifically, the effect of a soluble form of PrP(C)...

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Hlavní autoři: Jeon, Jae-Won, Park, Bum-Chan, Jung, Joon-Goo, Jang, Young-Soon, Shin, Eui-Cheol, Park, Young Woo
Médium: Artigo
Jazyk:Inglês
Vydáno: The Korean Association of Immunologists 2013
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3759712/
https://ncbi.nlm.nih.gov/pubmed/24009542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4110/in.2013.13.4.148
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