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Development of lacosamide for the treatment of partial-onset seizures

Lacosamide is an antiepileptic drug (AED) available in multiple formulations that was first approved in 2008 as adjunctive therapy for partial-onset seizures (POS) in adults. Unlike traditional sodium channel blockers affecting fast inactivation, lacosamide selectively enhances sodium channel slow i...

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Detalhes bibliográficos
Main Authors: Doty, Pamela, Hebert, David, Mathy, Francois-Xavier, Byrnes, William, Zackheim, James, Simontacchi, Kelly
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3759704/
https://ncbi.nlm.nih.gov/pubmed/23859801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/nyas.12213
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