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Pseudotyped Adeno-Associated Viral Vectors for Gene Transfer in Dermal Fibroblasts: Implications for Wound Healing Applications

BACKGROUND: Cell specific gene transfer and sustained transgene expression are goals of cutaneous gene therapy. Pseudotyping strategy with AAV vectors has the potential to confer unique cellular tropism and transduction efficiency. We hypothesize that pseudotyped AAV vectors have differential tropis...

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Detalhes bibliográficos
Main Authors: Balaji, Swathi, King, Alice, Dhamija, Yashu, Le, Louis D, Shaaban, Aimen F., Crombleholme, Timothy M., Keswani, Sundeep G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3759652/
https://ncbi.nlm.nih.gov/pubmed/23590866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jss.2013.03.051
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