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Creatine Kinase ATP and Phosphocreatine Energy Supply in a Single Kindred of Patients with Hypertrophic Cardiomyopathy

A lethal and extensively characterized familial form of hypertrophic cardiomyopathy (HC) is due to a point mutation (Arg403Gln) in the cardiac β-myosin heavy-chain (MHC) gene. Although this is associated with abnormal energy metabolism and progression to heart failure in an animal model, in vivo car...

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Detalhes bibliográficos
Main Authors: Abraham, M. Roselle, Bottomley, Paul A., Dimaano, Veronica Lea, Pinheiro, Aurelio, Steinberg, Angela, Traill, Thomas A., Abraham, Theodore P., Weiss, Robert G
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3759602/
https://ncbi.nlm.nih.gov/pubmed/23751935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.amjcard.2013.05.017
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