Tyrosine Phosphorylation of the orphan receptor ESDN/DCBLD2 serves as a scaffold for the signaling adaptor CrkL

A quantitative proteomics screen to identify substrates of the Src family of tyrosine kinases (SFKs) whose phosphorylation promotes CrkL-SH2 binding identified the known Crk-associated substrate (Cas) of Src as well as the orphan receptor ESDN. Mutagenesis analysis of ESDN’s seven intracellular tyro...

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Autores principales: Aten, Tyler M., Redmond, Miranda M., Weaver, Sheila O., Love, Collin C., Joy, Ryan M., Lapp, Aliya S., Rivera, Osvaldo D., Hinkle, Karen L., Ballif, Bryan A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3759512/
https://ncbi.nlm.nih.gov/pubmed/23770091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2013.05.064
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