notch3 is essential for oligodendrocyte development and vascular integrity in zebrafish

Mutations in the human NOTCH3 gene cause CADASIL syndrome (cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy). CADASIL is an inherited small vessel disease characterized by diverse clinical manifestations including vasculopathy, neurodegeneration and dementia...

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Bibliographic Details
Main Authors: Zaucker, Andreas, Mercurio, Sara, Sternheim, Nitzan, Talbot, William S., Marlow, Florence L.
Format: Artigo
Language:Inglês
Published: The Company of Biologists Limited 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3759344/
https://ncbi.nlm.nih.gov/pubmed/23720232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.012005
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