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Ethanol metabolism and oxidative stress are required for unfolded protein response activation and steatosis in zebrafish with alcoholic liver disease

Secretory pathway dysfunction and lipid accumulation (steatosis) are the two most common responses of hepatocytes to ethanol exposure and are major factors in the pathophysiology of alcoholic liver disease (ALD). However, the mechanisms by which ethanol elicits these cellular responses are not fully...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Tsedensodnom, Orkhontuya, Vacaru, Ana M., Howarth, Deanna L., Yin, Chunyue, Sadler, Kirsten C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Company of Biologists Limited 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3759341/
https://ncbi.nlm.nih.gov/pubmed/23798569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.012195
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