Involvement of Potassium Channels in Vasorelaxant Effect Induced by Valeriana prionophylla Standl. in Rat Mesenteric Artery

Assays in vitro and in vivo were performed on extract from roots and leaves from the Valeriana prionophylla Standl. (VPR and VPF, resp.). In phenylephrine (1 μM) precontracted rings, VPR (0.01–300 μg/mL) induced a concentration-dependent relaxation (maximum response (MR) = 75.4 ± 4.0%, EC(50) = 5.97...

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Hauptverfasser: Reis, Milena Ramos, de Oliveira Filho, Abrahão Alves, Rodrigues, Lilia Simone Urzedo, Araújo, Jaíse Paiva, Maciel, Priscilla Maria Pereira, de Albuquerque, Jamile Morais, Cehinel Filho, Valdir, Cáceres, Armando, Fregoneze, Josmara Bartolomei, de Medeiros, Isac Almeida, Silva, Darizy Flávia
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2013
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3759249/
https://ncbi.nlm.nih.gov/pubmed/24023569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/147670
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