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Interaction between two cholesterol metabolism genes influences memory: findings from the Wisconsin Registry for Alzheimer’s Prevention

The strongest genetic factor for late-onset Alzheimer’s disease (AD) is APOE; nine additional susceptibility genes have recently been identified. The effect of these genes is often assumed to be additive and polygenic scores are formed as a summary measure of risk. However, interactions between thes...

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Detalhes bibliográficos
Main Authors: Engelman, Corinne D., Koscik, Rebecca L., Jonaitis, Erin M., Okonkwo, Ozioma C., Hermann, Bruce P., La Rue, Asenath, Sager, Mark A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3759032/
https://ncbi.nlm.nih.gov/pubmed/23669301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-130482
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