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Cyanuric acid hydrolase: evolutionary innovation by structural concatenation

The cyanuric acid hydrolase, AtzD, is the founding member of a newly identified family of ring-opening amidases. We report the first X-ray structure for this family, which is a novel fold (termed the ‘Toblerone’ fold) that likely evolved via the concatenation of monomers of the trimeric YjgF superfa...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Peat, Thomas S, Balotra, Sahil, Wilding, Matthew, French, Nigel G, Briggs, Lyndall J, Panjikar, Santosh, Cowieson, Nathan, Newman, Janet, Scott, Colin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Publishing Ltd 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3758960/
https://ncbi.nlm.nih.gov/pubmed/23651355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.12249
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