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The Crystal Structure of the Signal Recognition Particle in Complex with its Receptor

Co-translational targeting of membrane and secretory proteins is mediated by the universally conserved Signal Recognition Particle (SRP). Together with its receptor (SR), SRP mediates the GTP-dependent delivery of translating ribosomes bearing signal sequences to translocons on the target membrane....

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Autors principals: Ataide, Sandro F., Schmitz, Nikolaus, Shen, Kuang, Ke, Ailong, Shan, Shu-ou, Doudna, Jennifer A., Ban, Nenad
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3758919/
https://ncbi.nlm.nih.gov/pubmed/21330537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1196473
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