Á lódáil...
HER3, p95HER2, and HER2 protein expression levels define multiple subtypes of HER2-positive metastatic breast cancer
Trastuzumab is effective in the treatment of HER2/neu over-expressing breast cancer, but not all patients benefit from it. In vitro data suggest a role for HER3 in the initiation of signaling activity involving the AKT–mTOR pathway leading to trastuzumab insensitivity. We sought to investigate the p...
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| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
Springer US
2013
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3758835/ https://ncbi.nlm.nih.gov/pubmed/23959396 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-013-2665-0 |
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