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Diggin’ on U(biquitin): A Novel Method for the Identification of Physiological E3 Ubiquitin Ligase Substrates

The ubiquitin-proteasome system (UPS) plays a central role in maintaining protein homeostasis, emphasized by a myriad of diseases that are associated with altered UPS function such as cancer, muscle-wasting, and neurodegeneration. Protein ubiquitination plays a central role in both the promotion of...

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Detalhes bibliográficos
Main Authors: Rubel, Carrie E., Schisler, Jonathan C., Hamlett, Eric D., DeKroon, Robert M., Gautel, Mathias, Alzate, Oscar, Patterson, Cam
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3758785/
https://ncbi.nlm.nih.gov/pubmed/23695782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12013-013-9624-6
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