DRD2/ANKK1 Taq1A polymorphism (rs1800497) has opposing effects on D(2/3) receptor binding in healthy controls and patients with major depressive disorder

The A1 allele of the DRD2/ANKK1 Taq1A polymorphism (rs1800497) is associated with reduced striatal D(2/3) receptor binding in healthy individuals (Con) as well as depression and addiction. However, the effect of rs1800497 on D(2/3) receptor binding in depressed patients as well as the SNP’s effect o...

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Autors principals: Savitz, Jonathan, Hodgkinson, Colin A., Martin-Soelch, Chantal, Shen, Pei-Hong, Szczepanik, Joanna, Nugent, Allison C., Herscovitch, Peter, Grace, Anthony A., Goldman, David, Drevets, Wayne C.
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3758772/
https://ncbi.nlm.nih.gov/pubmed/23683269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/S146114571300045X
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