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Diffusion Tensor Imaging Detects Areas of Abnormal White Matter Microstructure in Patients with Partial Ornithine Transcarbamylase Deficiency

BACKGROUND AND PURPOSE: OTCD, an X-linked disorder, is the most common of the UCDs. Neonatal onset is associated with uniformly poor outcome. Males with late-onset OTCD show deficits in executive function, motor planning, and working memory. A broad phenotype is observed in heterozygous females. A s...

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Autori principali: Gropman, A.L., Gertz, B., Shattuck, K., Kahn, I.L., Seltzer, R., Krivitsky, L., Van Meter, J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Neuroradiology 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3758695/
https://ncbi.nlm.nih.gov/pubmed/20488904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3174/ajnr.A2122
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