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Leptin Action in the Dorsomedial Hypothalamus Increases Sympathetic Tone to Brown Adipose Tissue in Spite of Systemic Leptin Resistance

Leptin regulates body weight in mice by decreasing appetite and increasing sympathetic nerve activity (SNA), which increases energy expenditure in interscapular brown adipose tissue (iBAT). Diet-induced obese mice (DIO) are resistant to the anorectic actions of leptin. We evaluated whether leptin st...

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書誌詳細
主要な著者: Enriori, Pablo J., Sinnayah, Puspha, Simonds, Stephanie E., Garcia Rudaz, Cecilia, Cowley, Michael A.
フォーマット: Artigo
言語:Inglês
出版事項: Society for Neuroscience 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3758545/
https://ncbi.nlm.nih.gov/pubmed/21865462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2336-11.2011
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