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The neural guidance receptor Plexin C1 delays melanoma progression
Plexin C1 is a type I transmembrane receptor with intrinsic R-Ras GTPase activity, which regulates cytoskeletal remodeling and adhesion in normal human melanocytes. Melanocytes are pigment-producing cells of the epidermis, precursors for melanoma, and express high levels of Plexin C1, which is lost...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3758461/ https://ncbi.nlm.nih.gov/pubmed/23160370 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.511 |
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