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The Limitations of Simple Gene Set Enrichment Analysis Assuming Gene Independence
Since its first publication in 2003, the Gene Set Enrichment Analysis (GSEA) method, based on the Kolmogorov-Smirnov statistic, has been heavily used, modified, and also questioned. Recently a simplified approach, using a one-sample t-test score to assess enrichment and ignoring gene-gene correlatio...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3758419/ https://ncbi.nlm.nih.gov/pubmed/23070592 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0962280212460441 |
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