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Signals that regulate the oncogenic fate of neural stem cells and progenitors

Brain tumors have frequently been associated with a neural stem cell (NSC) origin and contain stem-like tumor cells, so-called brain tumor stem cells (BTSCs) that share many features with normal NSCs. A stem cell state of BTSCs confers resistance to radiotherapy and treatment with alkylating agents....

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Swartling, Fredrik J., Bolin, Sara, Phillips, Joanna J., Persson, Anders I.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3758390/
https://ncbi.nlm.nih.gov/pubmed/23376224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2013.01.027
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