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Synergistic Effect of Mesangial Cell-Induced CXCL1 and TGF-β1 in Promoting Podocyte Loss in IgA Nephropathy

Podocyte loss has been reported to relate to disease severity and progression in IgA nephropathy (IgAN). However, the underlying mechanism for its role in IgAN remain unclear. Recent evidence has shown that IgA1 complexes from patients with IgAN could activate mesangial cells to induce soluble media...

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Detalhes bibliográficos
Main Authors: Zhu, Li, Zhang, Qingxian, Shi, Sufang, Liu, Lijun, Lv, Jicheng, Zhang, Hong
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3758267/
https://ncbi.nlm.nih.gov/pubmed/24023680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0073425
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