Parathyroid hormone reverses radiation induced hypovascularity in a murine model of distraction osteogenesis

BACKGROUND: Radiation treatment results in a severe diminution of osseous vascularity. Intermittent parathyroid hormone (PTH) has been shown to have an anabolic effect on osteogenesis, though its impact on angiogenesis remains unknown. In this murine model of distraction osteogenesis, we hypothesize...

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Main Authors: Kang, Stephen Y., Deshpande, Sagar S., Donneys, Alexis, Rodriguez, Joey J., Nelson, Noah S., Felice, Peter A., Chepeha, Douglas B., Buchman, Steven R.
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3758112/
https://ncbi.nlm.nih.gov/pubmed/23643680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2013.04.022
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