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Substratum Compliance Modulates Corneal Fibroblast to Myofibroblast Transformation

PURPOSE. The transformation of fibroblasts to myofibroblasts is critical to corneal wound healing, stromal haze formation, and scarring. It has recently been demonstrated that the provision of biomimetic substratum topographic cues inhibits the progression toward the myofibroblast phenotype under th...

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Main Authors: Dreier, Britta, Thomasy, Sara M., Mendonsa, Rima, Raghunathan, Vijay Krishna, Russell, Paul, Murphy, Christopher J.
Format: Artigo
Jezik:Inglês
Izdano: The Association for Research in Vision and Ophthalmology 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3757908/
https://ncbi.nlm.nih.gov/pubmed/23860754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.12-11575
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