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Self micro-emulsifying drug delivery system of tacrolimus: Formulation, in vitro evaluation and stability studies
BACKGROUND: Tacrolimus has poor solubility in water ranging from 4 to 12 μg/mL. The oral bio availabilities of tacrolimus is poor and exhibits high intra and inter-subject variability (4-89%, average 25%) in the liver and the kidney transplant recipients and in patients with renal impairment. AIM: T...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Medknow Publications & Media Pvt Ltd
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3757905/ https://ncbi.nlm.nih.gov/pubmed/24015381 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/2230-973X.114899 |
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